ID.
Any/all printers worth their salt should be able to accept and work with ID native files and PDF by now.
I'm a card carrying Adobe devotee and ID's functional similarity to Illustrator flattened out the learning curve.
My frustration at having to maintain a second OS (Classic) for the sake of a single app from an unappreciative company (Quark) lead me to first tryout ID.
The comments about other switchers had also picqued my interest in the app, but I dragged my heels for the same 'industry standard' reasons.
Finally gave it a spin one day and I was sold in no time - and I've never looked back.
Again, if your printer can't handle ID files, then do yourself a favour - get ID and find yourself a new (read: better) printer.